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Melanocortins
PT-141
- Purity
- >= 99% (HPLC)
- Form
- Lyophilised powder
- Origin
- United States
Manufactured for laboratory research. Not for human or veterinary use. Read full disclaimer →
PT-141 (bremelanotide) is a synthetic melanocortin-receptor agonist studied in research into MC4R signalling pathways in experimental models.
- Purity >= 99% (HPLC)
- Supplied as a lyophilised powder
- Independent batch identity and purity testing
- For laboratory research use only; not for human or veterinary use
What is PT-141?
PT-141 is bremelanotide, a synthetic cyclic heptapeptide and a melanocortin-receptor ligand structurally related to melanotan II. It has the molecular formula C50H68N14O10, a molecular weight of 1025.2 g/mol, and CAS number 189691-06-3. The sequence is Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH. It is supplied as a lyophilised solid strictly for laboratory research.
Kovalabs supplies PT-141 as a reference compound for in-vitro and pre-clinical investigation only. It is not a dietary supplement, a cosmetic, or a product for human or veterinary use, and nothing on this page describes or implies any effect, benefit or outcome in people.
Is PT-141 legal in the UK?
PT-141 (bremelanotide) is not a controlled drug under the Misuse of Drugs Act 1971, so it can be bought and held in the UK for legitimate laboratory research. It is supplied for research use only, not for human or veterinary consumption. The named licensed medicine containing bremelanotide is a separate, regulated product: this research material is a distinct reference chemical and is not that medicine, a generic, an alternative or a substitute. The buyer is responsible for lawful and appropriate use. See our research disclaimer.
How are PT-141 identity and quality assured?
Every batch is released only after independent identity and purity testing. Purity is assessed by HPLC at 99%, and identity is confirmed against the expected mass for C50H68N14O10. The molecule is verified against its published identifiers, including CAS 189691-06-3 and PubChem CID 9941379, so the material in the vial matches the compound described. A batch certificate of analysis is available on our CoA page. Not all material sold under this name is equivalent: a current CoA is how identity and purity are demonstrated rather than assumed.
What does the research on PT-141 investigate?
In the published literature PT-141 is studied as a melanocortin-receptor ligand, with interest in melanocortin-4 receptor (MC4R) signalling in laboratory and animal-model systems. That work characterises receptor pharmacology in pre-clinical settings only. None of it establishes a benefit, effect or outcome in humans, and this material is not a licensed medicine. PT-141 is not supplied for, and is not to be used for, any human application. Mechanistic detail belongs to the wider research area: see the melanocortins category.
Synthesis and supply
PT-141 is manufactured to research grade and shipped as a lyophilised powder, a white to off-white solid, with UK despatch. For laboratory handling it is reconstituted in a compatible solvent such as bacteriostatic water; reconstitution is a bench step and no route, dose or human application is described or intended. Store the lyophilised solid at -20C, kept dry and protected from light, and hold reconstituted material at 2-8C. Related melanocortin research compounds include Melanotan 2 and Melanotan 1, with the full range on the melanocortins category page. For laboratory research use only; not for human or veterinary use.
- 2D structure
- Product name
- PT-141
- Synonyms
- Bremelanotide, PT 141
- Sequence
- Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
- Molecular formula
- C50H68N14O10
- Molecular weight
- 1025.2 g/mol
- CAS number
- 189691-06-3
- PubChem CID
- 9941379
- Purity
- >= 99% (HPLC)
- Form
- Lyophilised powder
- Appearance
- White to off-white solid
- Solubility
- Bacteriostatic water
- Storage
- Lyophilised: store at -20C, dry and light-protected. Reconstituted: 2-8C.
- What is PT-141?
- PT-141 is bremelanotide, a synthetic cyclic heptapeptide and melanocortin-receptor ligand structurally related to melanotan II. Its molecular formula is C50H68N14O10, molecular weight 1025.2 g/mol, and CAS number 189691-06-3, with the sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH. Kovalabs supplies it as a lyophilised reference compound for laboratory research use only.
- Is PT-141 legal in the UK?
- PT-141 (bremelanotide) is not a controlled drug under the Misuse of Drugs Act 1971, so it can be bought and held in the UK for legitimate laboratory research. It is supplied strictly for research use only, not for human or veterinary consumption. The buyer is responsible for lawful and appropriate handling and use of the material.
- Is PT-141 for human use?
- No. PT-141 is supplied solely as a reference chemical for in-vitro and pre-clinical laboratory research. It is not a dietary supplement, a cosmetic or a product for human or veterinary use, and it is not supplied for and must not be used for any human application. No route, dose or human use is described, recommended or implied.
- Has PT-141 been shown to be safe or effective in humans?
- Nothing on this page makes any safety or efficacy claim. The published literature characterises PT-141 as a melanocortin-receptor ligand in laboratory and animal-model systems. Those are pre-clinical findings and do not establish a benefit, effect or outcome in people. PT-141 supplied by Kovalabs is a research material, not a licensed medicine.
- Is PT-141 sold for sexual or libido-related use?
- No. PT-141 is supplied for laboratory research use only. It is not sold for, marketed for, or to be used for any human purpose, including any sexual, arousal or libido-related use. Kovalabs makes no claim of any human effect. The material is a reference compound for non-clinical investigation and nothing more.
- Is PT-141 the same as the licensed bremelanotide medicine?
- No. The named licensed medicine containing bremelanotide is a separate, regulated pharmaceutical product. The PT-141 supplied here is a distinct research chemical for laboratory use only and is not that medicine, a generic, an alternative, a substitute or an equivalent. It is not approved or intended to treat, diagnose or affect any condition in humans or animals.
- What are the molecular identifiers for PT-141?
- PT-141 has the molecular formula C50H68N14O10 and a molecular weight of 1025.2 g/mol. Its CAS number is 189691-06-3 and its PubChem CID is 9941379. The peptide sequence is Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH. These identifiers let researchers confirm they are working with the correct compound.
- Is all PT-141 the same?
- No. Material sold under the same name can differ in identity and purity. That is why every Kovalabs batch is released only after independent testing, with purity assessed by HPLC at 99% and identity confirmed against the expected mass and published identifiers. A current certificate of analysis, available on our CoA page, is how purity and identity are demonstrated rather than assumed.
- How is PT-141 supplied and reconstituted?
- PT-141 is supplied as a lyophilised powder, a white to off-white solid, despatched from the UK. For laboratory handling it is reconstituted in a compatible solvent such as bacteriostatic water. Reconstitution is a bench preparation step only: no route of administration, dose or human use is described, recommended or implied by Kovalabs.
- How should PT-141 be stored?
- Store the lyophilised PT-141 solid at -20C, kept dry and protected from light, to maintain stability. Once reconstituted in a compatible solvent for laboratory work, hold the material at 2-8C. Proper storage helps preserve identity and purity over the working life of the vial. The compound is for laboratory research use only.
- Does PT-141 come with a certificate of analysis?
- Yes. Each batch is released after independent identity and purity testing, and a batch certificate of analysis is available on our CoA page. The CoA reports HPLC purity of 99% and confirms identity against the expected mass for C50H68N14O10, so researchers can verify the material before use.
- Is PT-141 a peptide?
- Yes. PT-141 (bremelanotide) is a synthetic cyclic heptapeptide, meaning it is a short chain of seven amino acid residues arranged in a ring. Its sequence is Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH. It is classified as a melanocortin-receptor ligand and is supplied as a lyophilised research-grade peptide for laboratory use only.
- How does PT-141 compare to Melanotan 2?
- Both are synthetic melanocortin peptides studied at the melanocortin receptors, and PT-141 is structurally related to melanotan II. They are nonetheless distinct molecules with different sequences and CAS numbers. This comparison describes what the molecules are as research chemicals only and does not describe or imply any human effect. See the melanocortins category for the full research range.
No third-party batch reports have been uploaded for this product yet. Reports are issued by independent labs after each manufacturing batch.
Calculator
Research planning only
Concentration5.00 mg/ml
Volume to draw0.050 ml
Insulin syringe (100 IU/ml)
5.0units
For research planning only. Not medical, dosing, or therapeutic advice. All Kovalabs products are research-use-only.
Store unreconstituted vials at −20°C for long-term, or refrigerated at 2-8°C for short-term use. Avoid repeated freeze-thaw cycles.
Reconstitute with bacteriostatic water down the inside wall of the vial; gently swirl to dissolve. Do not shake.
Once reconstituted, refrigerate at 2-8°C and use within 2-4 weeks. Discard if cloudy, discoloured, or particulate.