Is Semax intended for human use?

No. Semax is sold exclusively as a research chemical for in-vitro and pre-clinical laboratory work. It is not a medicine, has no UK marketing authorisation and is not intended or approved for human or veterinary use. Nothing on this page should be read as guidance for administration to people or animals. Please review our research disclaimer before purchase.

What are the molecular identifiers for Semax?

Semax has the molecular formula C37H51N9O10S, a molecular weight of 813.9 g/mol and CAS number 80714-61-0. Its PubChem CID is 9811102 and its peptide sequence is Met-Glu-His-Phe-Pro-Gly-Pro. These identifiers are printed on the batch certificate of analysis so the supplied material can be verified against public chemistry databases.

Is all Semax the same?

No. Purity and identity vary by supplier, so a certificate of analysis matters. Kovalabs releases each batch only after independent testing, with purity assessed at 99% by HPLC and identity confirmed against the expected mass for C37H51N9O10S. Batch CoAs are available from our CoA library, letting you trace each vial back to its test data.

What purity is Kovalabs Semax?

Kovalabs Semax is supplied at 99% purity as assessed by HPLC, with identity confirmed against the expected mass for the C37H51N9O10S formula. Each batch is released after independent identity and purity testing, and the certificate of analysis is available from our CoA library so you can confirm the figures for the specific lot you receive.

How is Semax supplied and reconstituted?

Semax is supplied as a white to off-white lyophilised powder. For bench preparation it is commonly reconstituted with bacteriostatic water, which Kovalabs also stocks, to give a working solution for laboratory research. This describes a standard research-bench step only and is not guidance for any use in humans or animals.

How should Semax be stored?

Store the lyophilised Semax powder at -20C, kept dry and protected from light, where it is stable for long-term holding. Once reconstituted, keep the solution at 2-8C and use it within a short working window. Proper cold storage preserves peptide integrity for laboratory research and helps the material match the identity and purity stated on its certificate of analysis.

Where can I buy Semax in the UK?

Kovalabs supplies Semax for laboratory research within the UK, despatched from the UK with a batch certificate of analysis. It is sold as a research chemical only, not for human or veterinary use. You can find related research materials in our neuropeptides category, and our research disclaimer sets out the supply terms in full.

Is Semax a peptide or a steroid?

Semax is a peptide, not a steroid. It is a synthetic heptapeptide of seven amino acids based on the ACTH (4-10) fragment with a C-terminal Pro-Gly-Pro tail, sequence Met-Glu-His-Phe-Pro-Gly-Pro. Steroids are a different chemical class built on a sterol ring system, so the two are structurally unrelated research compounds.

How does Semax compare with Selank?

Both Semax and Selank are short synthetic research peptides studied in neuropeptide pathways, but they are distinct molecules with different sequences and origins. Semax derives from the ACTH (4-10) fragment, while Selank derives from the immunopeptide tuftsin. They are supplied as separate research chemicals. See the Selank product page to compare their identifiers and specifications.

Is a certificate of analysis provided with Semax?

Yes. Every batch of Semax ships with a certificate of analysis recording its HPLC purity, identity confirmation and the verified identifiers, including CAS 80714-61-0 and PubChem CID 9811102. CoAs are available from our CoA library so you can match the documentation to the lot number on your vial before using the material for research.

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Semax

Name: Semax
Brand: Kovalabs
SKU: XA5-10MG
Price: 29.99 GBP
Availability: InStock
Rating: 5 (20 reviews)

520 reviews

£29.99

In stockFast UK dispatch, Mon to Fri

Pack10mg

Lab tested: ISO 17025
Batch: SMX10-274
Form: Lyophilised powder

Manufactured for laboratory research. Not for human or veterinary use. Read full disclaimer →

Description

Semax is a synthetic heptapeptide derived from a fragment of adrenocorticotropic hormone (ACTH 4-10), studied in research into BDNF expression and neuropeptide-signalling pathways in experimental models.

Purity >= 99% (HPLC)
Supplied as a lyophilised powder
Independent batch identity and purity testing
For laboratory research use only; not for human or veterinary use

What is Semax?

Semax is a synthetic heptapeptide based on a fragment of adrenocorticotropic hormone (ACTH 4-10) extended with a C-terminal Pro-Gly-Pro tail. Its sequence is Met-Glu-His-Phe-Pro-Gly-Pro, molecular formula C37H51N9O10S and molecular weight 813.9 g/mol. It is supplied as a lyophilised powder for laboratory research only.

Developed from Russian neuropeptide research, Semax is one of a family of short ACTH-derived peptides. Kovalabs supplies it strictly as a reference compound for in-vitro and pre-clinical investigation. The alias "SEM" is sometimes used for it. It is not a medicine and is not intended for human or veterinary use.

Is Semax legal in the UK?

Semax is not a controlled drug under the Misuse of Drugs Act 1971, so possession of the research material itself is not an offence. It holds no UK marketing authorisation as a medicine and is not approved for human or veterinary use. Kovalabs supplies Semax for laboratory research only; it cannot be sold or used for human consumption, and the buyer is responsible for compliant handling. See our research disclaimer for full terms.

How is identity and quality assured?

Every batch of Semax is released only after independent identity and purity testing. Purity is assessed at 99% by HPLC and identity is confirmed against the expected mass for C37H51N9O10S. The verified identifiers are CAS 80714-61-0 and PubChem CID 9811102, matching the Met-Glu-His-Phe-Pro-Gly-Pro sequence. Batch certificates of analysis are available from our CoA library so each vial can be traced to its test data.

What does the research on Semax investigate?

The published literature investigates Semax in relation to BDNF-related signalling and neuropeptide pathways in cell and animal models. This is the area researchers explore; none of it establishes a benefit, cognitive effect, neuroprotective outcome or any result in humans, and Semax is not a licensed medicine. For the mechanistic detail and a structured review of the study designs, see the Semax research monograph.

Synthesis and supply

Semax is supplied as a white to off-white lyophilised solid. For bench work it is typically reconstituted with bacteriostatic water, which Kovalabs also stocks. Store the lyophilised powder at -20C, dry and protected from light, and hold reconstituted material at 2-8C. Browse the full neuropeptides category or compare related research peptides such as Selank and DSIP. For laboratory research use only; not for human or veterinary use.

External resources for researchers

Specifications

2D structure
Product name: Semax
Synonyms: ACTH (4-10) Pro-Gly-Pro
Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
Molecular formula: C37H51N9O10S
Molecular weight: 813.9 g/mol
CAS number: 80714-61-0
PubChem CID: 9811102
Purity: ≥ 99% (HPLC)
Form: Lyophilised powder
Appearance: White to off-white solid
Solubility: Bacteriostatic water
Storage: Lyophilised: store at -20C, dry and light-protected. Reconstituted: 2-8C.

Testing reports

Semax 10mg
SMX10-274
99.38%
Peptide purity
Purity (HPLC)
99.38%
Net peptide content
10.24 mg
Identity (HPLC-RTM)
Semax
Fentanyl screen
Not Detected
ILS LabsTested 18 Aug 2026

Common questions

What is Semax?: Semax is a synthetic heptapeptide derived from a fragment of adrenocorticotropic hormone (ACTH 4-10) with an added C-terminal Pro-Gly-Pro tail. Its sequence is Met-Glu-His-Phe-Pro-Gly-Pro, molecular formula C37H51N9O10S and molecular weight 813.9 g/mol. Kovalabs supplies it as a lyophilised powder strictly as a reference compound for laboratory research, not as a medicine.
Is Semax legal in the UK?: Semax is not a controlled drug under the Misuse of Drugs Act 1971, so possession of the research material is not in itself an offence. It holds no UK marketing authorisation and is not approved for human or veterinary use. Kovalabs supplies it for laboratory research only; it cannot be sold or used for human consumption, and the buyer is responsible for lawful, compliant handling.
Is Semax intended for human use?: No. Semax is sold exclusively as a research chemical for in-vitro and pre-clinical laboratory work. It is not a medicine, has no UK marketing authorisation and is not intended or approved for human or veterinary use. Nothing on this page should be read as guidance for administration to people or animals. Please review our research disclaimer before purchase.
What does the research on Semax investigate?: The literature examines Semax, an ACTH (4-10) analog, in relation to neuropeptide signalling and BDNF-related pathways in laboratory models. That is the research area being explored. None of it demonstrates an effect or outcome in humans. The mechanistic depth and citation review are handed off to the Semax research monograph rather than covered here.
What are the molecular identifiers for Semax?: Semax has the molecular formula C37H51N9O10S, a molecular weight of 813.9 g/mol and CAS number 80714-61-0. Its PubChem CID is 9811102 and its peptide sequence is Met-Glu-His-Phe-Pro-Gly-Pro. These identifiers are printed on the batch certificate of analysis so the supplied material can be verified against public chemistry databases.
Is all Semax the same?: No. Purity and identity vary by supplier, so a certificate of analysis matters. Kovalabs releases each batch only after independent testing, with purity assessed at 99% by HPLC and identity confirmed against the expected mass for C37H51N9O10S. Batch CoAs are available from our CoA library, letting you trace each vial back to its test data.
What purity is Kovalabs Semax?: Kovalabs Semax is supplied at 99% purity as assessed by HPLC, with identity confirmed against the expected mass for the C37H51N9O10S formula. Each batch is released after independent identity and purity testing, and the certificate of analysis is available from our CoA library so you can confirm the figures for the specific lot you receive.
How is Semax supplied and reconstituted?: Semax is supplied as a white to off-white lyophilised powder. For bench preparation it is commonly reconstituted with bacteriostatic water, which Kovalabs also stocks, to give a working solution for laboratory research. This describes a standard research-bench step only and is not guidance for any use in humans or animals.
How should Semax be stored?: Store the lyophilised Semax powder at -20C, kept dry and protected from light, where it is stable for long-term holding. Once reconstituted, keep the solution at 2-8C and use it within a short working window. Proper cold storage preserves peptide integrity for laboratory research and helps the material match the identity and purity stated on its certificate of analysis.
Where can I buy Semax in the UK?: Kovalabs supplies Semax for laboratory research within the UK, despatched from the UK with a batch certificate of analysis. It is sold as a research chemical only, not for human or veterinary use. You can find related research materials in our neuropeptides category, and our research disclaimer sets out the supply terms in full.
Is Semax a peptide or a steroid?: Semax is a peptide, not a steroid. It is a synthetic heptapeptide of seven amino acids based on the ACTH (4-10) fragment with a C-terminal Pro-Gly-Pro tail, sequence Met-Glu-His-Phe-Pro-Gly-Pro. Steroids are a different chemical class built on a sterol ring system, so the two are structurally unrelated research compounds.
How does Semax compare with Selank?: Both Semax and Selank are short synthetic research peptides studied in neuropeptide pathways, but they are distinct molecules with different sequences and origins. Semax derives from the ACTH (4-10) fragment, while Selank derives from the immunopeptide tuftsin. They are supplied as separate research chemicals. See the Selank product page to compare their identifiers and specifications.
Is a certificate of analysis provided with Semax?: Yes. Every batch of Semax ships with a certificate of analysis recording its HPLC purity, identity confirmation and the verified identifiers, including CAS 80714-61-0 and PubChem CID 9811102. CoAs are available from our CoA library so you can match the documentation to the lot number on your vial before using the material for research.

What is Semax?

Is Semax legal in the UK?

How is identity and quality assured?

What does the research on Semax investigate?

Synthesis and supply

Semax

What is Semax?

Is Semax legal in the UK?

How is identity and quality assured?

What does the research on Semax investigate?

Synthesis and supply

External resources for researchers

Before you continue.

Semax

What is Semax?

Is Semax legal in the UK?

How is identity and quality assured?

What does the research on Semax investigate?

Synthesis and supply

External resources for researchers

Reviews

Reviews