Semax

2D structure

Product name

Semax

Synonyms

ACTH (4-10) Pro-Gly-Pro

Sequence

Met-Glu-His-Phe-Pro-Gly-Pro

Molecular formula

C37H51N9O10S

Molecular weight

813.9 g/mol

CAS number

80714-61-0

PubChem CID

9811102

Purity

>= 99% (HPLC)

Form

Lyophilised powder

Appearance

White to off-white solid

Solubility

Bacteriostatic water

Storage

Lyophilised: store at -20C, dry and light-protected. Reconstituted: 2-8C.

What is Semax?

Semax is a synthetic heptapeptide derived from a fragment of adrenocorticotropic hormone (ACTH 4-10) with an added C-terminal Pro-Gly-Pro tail. Its sequence is Met-Glu-His-Phe-Pro-Gly-Pro, molecular formula C37H51N9O10S and molecular weight 813.9 g/mol. Kovalabs supplies it as a lyophilised powder strictly as a reference compound for laboratory research, not as a medicine.

Is Semax legal in the UK?

Semax is not a controlled drug under the Misuse of Drugs Act 1971, so possession of the research material is not in itself an offence. It holds no UK marketing authorisation and is not approved for human or veterinary use. Kovalabs supplies it for laboratory research only; it cannot be sold or used for human consumption, and the buyer is responsible for lawful, compliant handling.

Is Semax intended for human use?

No. Semax is sold exclusively as a research chemical for in-vitro and pre-clinical laboratory work. It is not a medicine, has no UK marketing authorisation and is not intended or approved for human or veterinary use. Nothing on this page should be read as guidance for administration to people or animals. Please review our research disclaimer before purchase.

Has Semax been shown to be safe or effective in humans?

No. The published work on Semax sits in cell and animal models and investigates pathways such as BDNF-related signalling. These are research observations only and do not establish any benefit, cognitive effect, neuroprotective outcome, safety profile or efficacy in humans. Semax is not a licensed medicine. For the study-design detail, see the Semax research monograph linked on this page.

What does the research on Semax investigate?

The literature examines Semax, an ACTH (4-10) analog, in relation to neuropeptide signalling and BDNF-related pathways in laboratory models. That is the research area being explored. None of it demonstrates an effect or outcome in humans. The mechanistic depth and citation review are handed off to the Semax research monograph rather than covered here.

What are the molecular identifiers for Semax?

Semax has the molecular formula C37H51N9O10S, a molecular weight of 813.9 g/mol and CAS number 80714-61-0. Its PubChem CID is 9811102 and its peptide sequence is Met-Glu-His-Phe-Pro-Gly-Pro. These identifiers are printed on the batch certificate of analysis so the supplied material can be verified against public chemistry databases.

Is all Semax the same?

No. Purity and identity vary by supplier, so a certificate of analysis matters. Kovalabs releases each batch only after independent testing, with purity assessed at 99% by HPLC and identity confirmed against the expected mass for C37H51N9O10S. Batch CoAs are available from our CoA library, letting you trace each vial back to its test data.

What purity is Kovalabs Semax?

Kovalabs Semax is supplied at 99% purity as assessed by HPLC, with identity confirmed against the expected mass for the C37H51N9O10S formula. Each batch is released after independent identity and purity testing, and the certificate of analysis is available from our CoA library so you can confirm the figures for the specific lot you receive.

How is Semax supplied and reconstituted?

Semax is supplied as a white to off-white lyophilised powder. For bench preparation it is commonly reconstituted with bacteriostatic water, which Kovalabs also stocks, to give a working solution for laboratory research. This describes a standard research-bench step only and is not guidance for any use in humans or animals.

How should Semax be stored?

Store the lyophilised Semax powder at -20C, kept dry and protected from light, where it is stable for long-term holding. Once reconstituted, keep the solution at 2-8C and use it within a short working window. Proper cold storage preserves peptide integrity for laboratory research and helps the material match the identity and purity stated on its certificate of analysis.

Where can I buy Semax in the UK?

Kovalabs supplies Semax for laboratory research within the UK, despatched from the UK with a batch certificate of analysis. It is sold as a research chemical only, not for human or veterinary use. You can find related research materials in our neuropeptides category, and our research disclaimer sets out the supply terms in full.

Is Semax a peptide or a steroid?

Semax is a peptide, not a steroid. It is a synthetic heptapeptide of seven amino acids based on the ACTH (4-10) fragment with a C-terminal Pro-Gly-Pro tail, sequence Met-Glu-His-Phe-Pro-Gly-Pro. Steroids are a different chemical class built on a sterol ring system, so the two are structurally unrelated research compounds.

How does Semax compare with Selank?

Both Semax and Selank are short synthetic research peptides studied in neuropeptide pathways, but they are distinct molecules with different sequences and origins. Semax derives from the ACTH (4-10) fragment, while Selank derives from the immunopeptide tuftsin. They are supplied as separate research chemicals. See the Selank product page to compare their identifiers and specifications.

Is a certificate of analysis provided with Semax?

Yes. Every batch of Semax ships with a certificate of analysis recording its HPLC purity, identity confirmation and the verified identifiers, including CAS 80714-61-0 and PubChem CID 9811102. CoAs are available from our CoA library so you can match the documentation to the lot number on your vial before using the material for research.

No third-party batch reports have been uploaded for this product yet. Reports are issued by independent labs after each manufacturing batch.