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Metabolic
Cagrilintide
- Purity
- >= 99% (HPLC)
- Form
- Lyophilised powder
- Origin
- United States
Manufactured for laboratory research. Not for human or veterinary use. Read full disclaimer →
Cagrilintide is a synthetic long-acting amylin receptor agonist studied in research into amylin-receptor signalling and metabolic-regulation pathways in experimental models.
- Purity >= 99% (HPLC)
- Supplied as a lyophilised powder
- Independent batch identity and purity testing
- For laboratory research use only; not for human or veterinary use
What is cagrilintide?
Cagrilintide (development code AM833) is a long-acting synthetic analog of the peptide hormone amylin. It carries the molecular formula C194H312N54O59S2 with a molecular weight of 4409 g/mol and the CAS number 1415456-99-3. Kovalabs supplies it as a lyophilised powder for laboratory research use only. It is not a medicine and is not for human or veterinary use.
As a structural analog it is studied alongside other amylin and calcitonin-receptor reference compounds. The name CagriSema refers to a separate investigational fixed-combination of cagrilintide with semaglutide; the term identifies that pairing as a molecular combination and does not describe any protocol, effect or outcome. Cagrilintide is also frequently catalogued next to retatrutide as a distinct metabolic-research peptide.
Is cagrilintide legal in the UK?
Cagrilintide is not a controlled drug under the Misuse of Drugs Act 1971, and it can be supplied lawfully in the UK as a research chemical. It holds no marketing authorisation from the MHRA, so it is not a licensed medicine and may not be sold or used for human or veterinary consumption. Kovalabs supplies it strictly for in-vitro and laboratory research. The purchaser is responsible for lawful handling under applicable regulations. See our research disclaimer for full terms.
How is identity and quality assured?
Every batch is released only after independent identity and purity testing. Purity is assessed by HPLC at >= 99% and identity is confirmed against the expected mass. The verified identifiers are CAS 1415456-99-3, molecular formula C194H312N54O59S2, molecular weight 4409 g/mol and PubChem CID 171397054. Not all material sold under this name is equivalent: a current Certificate of Analysis is the only way to confirm what a vial actually contains. Batch certificates are available on our CoA page.
What does the research on cagrilintide investigate?
The published literature investigates cagrilintide as a tool compound in amylin and calcitonin-receptor signalling and in metabolic-pathway model systems. These are pre-clinical, in-vitro and animal-model observations. None of this establishes a benefit, effect or outcome in humans, and cagrilintide is not a licensed medicine. For a referenced, study-design-only overview of the amylin-receptor research area, see our cagrilintide and amylin research monograph.
Synthesis and supply
Cagrilintide is supplied as a lyophilised (freeze-dried) white to off-white solid. For laboratory handling it is typically reconstituted with a compatible solvent such as bacteriostatic water before use in non-clinical assays. Store the lyophilised powder at -20C, kept dry and protected from light; hold reconstituted material at 2-8C. Browse the full metabolic research category or related reference peptides including retatrutide, MOTS-c and AOD-9604. All items are for laboratory research use only.
- 2D structure
- Product name
- Cagrilintide
- Synonyms
- AM833
- Molecular formula
- C194H312N54O59S2
- Molecular weight
- 4409 g/mol
- CAS number
- 1415456-99-3
- PubChem CID
- 171397054
- Purity
- >= 99% (HPLC)
- Form
- Lyophilised powder
- Appearance
- White to off-white solid
- Solubility
- Bacteriostatic water
- Storage
- Lyophilised: store at -20C, dry and light-protected. Reconstituted: 2-8C.
- What is cagrilintide?
- Cagrilintide (development code AM833) is a long-acting synthetic analog of the peptide hormone amylin. It has the molecular formula C194H312N54O59S2, a molecular weight of 4409 g/mol and CAS number 1415456-99-3. Kovalabs supplies it as a lyophilised powder for laboratory research use only. It is not a medicine and is not intended for human or veterinary use.
- Is cagrilintide a peptide?
- Yes. Cagrilintide is a synthetic peptide, specifically a long-acting analog of human amylin. It is a single defined molecule with the formula C194H312N54O59S2 and a molecular weight of 4409 g/mol. It is supplied as a lyophilised solid as a reference compound for non-clinical laboratory research, not as a therapeutic product.
- Is cagrilintide legal in the UK?
- Cagrilintide is not a controlled drug under the Misuse of Drugs Act 1971 and can be supplied lawfully in the UK as a research chemical. It has no MHRA marketing authorisation, so it is not a licensed medicine and may not be sold or used for human or veterinary consumption. Kovalabs supplies it for laboratory research only, and the purchaser is responsible for lawful handling.
- Is cagrilintide for human use?
- No. Cagrilintide is supplied by Kovalabs for in-vitro and laboratory research use only. It is not a licensed medicine, it has no marketing authorisation, and it is not intended or supplied for human or veterinary use, ingestion or administration. Nothing on this page should be read as describing or recommending any human application.
- Has cagrilintide been shown to be safe or effective in humans?
- No such claim is made here. The published literature on cagrilintide consists of pre-clinical, in-vitro and animal-model work investigating amylin and calcitonin-receptor signalling. None of this establishes a benefit, effect, safety profile or outcome in humans, and cagrilintide is not a licensed medicine. It is supplied solely as a reference compound for non-clinical research.
- What does the research on cagrilintide investigate?
- The literature investigates cagrilintide as a tool compound in amylin and calcitonin-receptor signalling and in metabolic-pathway model systems, using pre-clinical and laboratory models. These are research-context observations only and do not establish any human benefit, effect or outcome. A referenced, study-design-only overview is available in our cagrilintide and amylin research monograph linked from this page.
- What is the molecular formula and CAS number of cagrilintide?
- Cagrilintide has the molecular formula C194H312N54O59S2, a molecular weight of 4409 g/mol and CAS number 1415456-99-3. Its PubChem CID is 171397054 and it is also known by the development code AM833. These identifiers are stated on each Certificate of Analysis so the supplied material can be confirmed against the expected structure.
- Is all cagrilintide the same?
- No. Material sold under the same name can differ in purity and identity between suppliers and batches. The only reliable way to confirm what a vial contains is a current Certificate of Analysis. Kovalabs releases each batch after independent testing, with purity assessed by HPLC at >= 99% and identity confirmed against the expected mass. Batch certificates are available on our CoA page.
- What is CagriSema, and how does it relate to cagrilintide?
- CagriSema is the name for an investigational fixed-combination of cagrilintide with semaglutide. The term identifies that molecular pairing; it does not describe any protocol, effect or outcome and is used here only to clarify identity. Kovalabs supplies cagrilintide as a single research peptide, not as a combination product, and strictly for laboratory research use only.
- What is the difference between cagrilintide and retatrutide?
- They are distinct molecules. Cagrilintide is a long-acting amylin analog (formula C194H312N54O59S2). Retatrutide is a separate multi-receptor peptide with its own structure and identifiers. Both are catalogued as metabolic-research reference compounds, but they are different chemical entities. This comparison concerns molecular identity only and implies no effect or outcome in humans.
- How is cagrilintide supplied and reconstituted?
- Cagrilintide is supplied as a lyophilised (freeze-dried) white to off-white powder. For non-clinical laboratory work it is typically reconstituted with a compatible solvent such as bacteriostatic water before use in assays. This describes laboratory handling only; the material is not for human or veterinary administration and is provided for research use only.
- How should cagrilintide be stored?
- Store the lyophilised powder at -20C, kept dry and protected from light, to maintain stability. Once reconstituted, hold the solution at 2-8C and use within the working window appropriate to your protocol. Correct cold storage helps preserve peptide integrity for laboratory research. The product is for laboratory research use only, not for human or veterinary use.
- Where can I buy cagrilintide in the UK?
- Kovalabs supplies cagrilintide in the UK as a research-grade lyophilised peptide with a Certificate of Analysis per batch, HPLC purity of >= 99% and UK despatch. It is sold strictly for laboratory research use only and is not for human or veterinary use. Verified identifiers and batch certificates are provided so the supplied material can be confirmed before use.
- Does cagrilintide have a Certificate of Analysis?
- Yes. Every batch is released only after independent identity and purity testing, and a Certificate of Analysis is provided. The CoA states the verified identifiers (CAS 1415456-99-3, formula C194H312N54O59S2, molecular weight 4409 g/mol, PubChem CID 171397054) along with the HPLC purity result. Batch certificates are available on our CoA page.
No third-party batch reports have been uploaded for this product yet. Reports are issued by independent labs after each manufacturing batch.
Calculator
Research planning only
Concentration2.50 mg/ml
Volume to draw0.100 ml
Insulin syringe (100 IU/ml)
10.0units
For research planning only. Not medical, dosing, or therapeutic advice. All Kovalabs products are research-use-only.
Store unreconstituted vials at −20°C for long-term, or refrigerated at 2-8°C for short-term use. Avoid repeated freeze-thaw cycles.
Reconstitute with bacteriostatic water down the inside wall of the vial; gently swirl to dissolve. Do not shake.
Once reconstituted, refrigerate at 2-8°C and use within 2-4 weeks. Discard if cloudy, discoloured, or particulate.