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GH Axis
Sermorelin
- Purity
- >= 99% (HPLC)
- Form
- Lyophilised powder
- Origin
- United States
Manufactured for laboratory research. Not for human or veterinary use. Read full disclaimer →
Sermorelin is a synthetic analogue of the first 29 amino acids of growth-hormone-releasing hormone (GHRH 1-29), studied in research into GHRH-receptor signalling and the GH axis in experimental models.
- Purity >= 99% (HPLC)
- Supplied as a lyophilised powder
- Independent batch identity and purity testing
- For laboratory research use only; not for human or veterinary use
What is Sermorelin?
Sermorelin is a synthetic 29-amino-acid peptide corresponding to the first 29 residues of growth-hormone-releasing hormone, GHRH (1-29). It carries the molecular formula C149H246N44O42S, a molecular weight of 3357.9 g/mol and CAS number 86168-78-7. Kovalabs supplies it as a lyophilised research peptide for laboratory use only.
It is also catalogued as GRF (1-29) and as the salt form Sermorelin acetate. In research settings it is studied as a GHRH-receptor agonist within the somatotropic (GH) axis. PubChem lists it under CID 16132413.
Is Sermorelin legal in the UK?
Sermorelin is not a controlled drug under the Misuse of Drugs Act 1971, so it is legal to buy and hold in the UK as a research chemical. Kovalabs supplies it for laboratory research use only. It is not a medicine, is not authorised for human or veterinary use, and cannot be sold for human consumption. The purchaser is responsible for lawful handling and for compliance with the rules of their institution and jurisdiction.
Is Sermorelin the same as the licensed medicine?
No. Sermorelin has existed in licensed medicinal forms in some territories, but the material sold here is a distinct research chemical. It is not that medicine, not a generic, alternative, substitute or equivalent of it, and is not offered to diagnose, treat, prevent or manage any condition. It is supplied solely as a reference compound for non-clinical laboratory work.
How is identity and quality assured?
Each batch is released after independent analysis. Purity is assessed by HPLC at 99% or greater, and identity is confirmed against the expected mass and the verified identifiers: CAS 86168-78-7, formula C149H246N44O42S, molecular weight 3357.9 g/mol and PubChem CID 16132413. A batch certificate of analysis is available on the CoA page. Not all material described as sermorelin is equivalent, so the CoA is the reference point for what arrives.
What does the research on Sermorelin investigate?
The published literature studies Sermorelin as a GHRH-receptor agonist acting on the GH axis in pre-clinical and in-vitro models, alongside its use as an analytical reference in anti-doping work. None of this establishes a benefit, effect or outcome in humans, and it is not a licensed medicine. The mechanistic and evidence detail sits in the Sermorelin GHRH research monograph; this product page does not assess clinical evidence. See the research disclaimer for the terms of supply.
Synthesis and supply
Sermorelin is supplied as a white to off-white lyophilised powder. For bench work it is typically reconstituted with a solvent such as bacteriostatic water, a standard laboratory step. Store the lyophilised solid at -20C, kept dry and protected from light; hold reconstituted material at 2-8C. It sits in the GH-axis category alongside related research peptides including Tesamorelin, Ipamorelin and CJC-1295 (no DAC). For laboratory research use only; not for human or veterinary use.
External resources for researchers
- 2D structure
- Product name
- Sermorelin
- Synonyms
- GRF (1-29), Sermorelin acetate
- Molecular formula
- C149H246N44O42S
- Molecular weight
- 3357.9 g/mol
- CAS number
- 86168-78-7
- PubChem CID
- 16132413
- Purity
- >= 99% (HPLC)
- Form
- Lyophilised powder
- Appearance
- White to off-white solid
- Solubility
- Bacteriostatic water
- Storage
- Lyophilised: store at -20C, dry and light-protected. Reconstituted: 2-8C.
- What is Sermorelin?
- Sermorelin is a synthetic 29-amino-acid peptide corresponding to the first 29 residues of growth-hormone-releasing hormone, GHRH (1-29). It is studied in research as a GHRH-receptor agonist within the GH axis. Kovalabs supplies it as a lyophilised research peptide for laboratory research use only, not for human or veterinary use.
- Is Sermorelin legal in the UK?
- Sermorelin is not a controlled drug under the Misuse of Drugs Act 1971, so it is legal to buy and hold in the UK as a research chemical. Kovalabs supplies it for laboratory research use only. It is not a medicine, cannot be sold for human consumption, and the purchaser is responsible for lawful handling and for compliance with their institution and jurisdiction.
- Is Sermorelin intended for human use?
- No. Sermorelin is supplied strictly for laboratory research use only. It is not for human or veterinary use, is not a dietary supplement or cosmetic, and nothing about its supply implies any human, cosmetic or veterinary application. It is offered solely as a reference compound for non-clinical investigation.
- Is Sermorelin the same as the licensed medicine?
- No. Sermorelin has existed in licensed medicinal forms in some territories, but the material sold here is a distinct research chemical. It is not that medicine, not a generic, alternative, substitute or equivalent of it, and is not offered to diagnose, treat, prevent or manage any condition. It is supplied only as a non-clinical reference compound.
- Has Sermorelin been shown to be safe or effective in humans?
- This product page makes no such claim. The published literature studies Sermorelin in pre-clinical and in-vitro models and as an analytical reference, but none of that establishes a benefit, effect, safety profile or outcome in humans. It is not a licensed medicine. Background sits in the Sermorelin GHRH research monograph linked from the page.
- What does the research on Sermorelin investigate?
- Research describes Sermorelin as a GHRH-receptor agonist acting on the somatotropic (GH) axis in laboratory models, and uses it as a reference standard in anti-doping analysis. These are research-context observations only; they do not establish a human benefit or effect. The mechanistic detail is covered in the linked GHRH research monograph, not on this product page.
- What are the molecular identifiers for Sermorelin?
- Sermorelin has the molecular formula C149H246N44O42S and a molecular weight of 3357.9 g/mol. It is identified by CAS number 86168-78-7 and PubChem CID 16132413. It corresponds to GHRH (1-29), the first 29 residues of growth-hormone-releasing hormone, and is also catalogued as GRF (1-29).
- Is all Sermorelin the same?
- No. Material described as sermorelin can differ in purity and identity between suppliers. Kovalabs releases each batch after independent testing, with purity at 99% or greater by HPLC and identity confirmed against the expected mass. The batch certificate of analysis is the reference point and is available on the CoA page.
- How is Sermorelin supplied and reconstituted?
- Sermorelin is supplied as a white to off-white lyophilised powder. For bench work it is typically reconstituted with a solvent such as bacteriostatic water, a standard laboratory step. The vial strength is a product specification, not a usage instruction. It is supplied for laboratory research use only.
- How should Sermorelin be stored?
- Store the lyophilised solid at -20C, kept dry and protected from light. Once reconstituted for research work, hold the material at 2-8C. Correct storage helps preserve identity and purity over the working period. It remains for laboratory research use only; not for human or veterinary use.
- Is a certificate of analysis available for Sermorelin?
- Yes. Each batch is released with an independent certificate of analysis covering identity and HPLC purity, confirming purity at 99% or greater. The CoA documents the verified identifiers including CAS 86168-78-7 and the expected mass. Current certificates are published on the CoA page.
- What is the difference between Sermorelin and Tesamorelin?
- Both are GHRH-related research peptides in the GH-axis category, but they are distinct molecules with different sequences and identifiers. Sermorelin is GHRH (1-29); Tesamorelin is a separate stabilised GHRH analogue sold as its own research compound. Each is supplied for laboratory research use only, with its own batch CoA.
- Is Sermorelin a peptide or a steroid?
- Sermorelin is a peptide, not a steroid. It is a chain of 29 amino acids corresponding to GHRH (1-29), with the molecular formula C149H246N44O42S. It is supplied as a lyophilised research peptide for laboratory research use only, not for human or veterinary use.
- Where can I buy Sermorelin in the UK?
- Kovalabs supplies Sermorelin in the UK as a research peptide, despatched from the UK with a batch certificate of analysis. It is sold for laboratory research use only and cannot be supplied for human consumption. See the GH-axis category for related research peptides such as Ipamorelin and CJC-1295 (no DAC).
No third-party batch reports have been uploaded for this product yet. Reports are issued by independent labs after each manufacturing batch.
Calculator
Research planning only
Concentration2.50 mg/ml
Volume to draw0.100 ml
Insulin syringe (100 IU/ml)
10.0units
For research planning only. Not medical, dosing, or therapeutic advice. All Kovalabs products are research-use-only.
Store unreconstituted vials at −20°C for long-term, or refrigerated at 2-8°C for short-term use. Avoid repeated freeze-thaw cycles.
Reconstitute with bacteriostatic water down the inside wall of the vial; gently swirl to dissolve. Do not shake.
Once reconstituted, refrigerate at 2-8°C and use within 2-4 weeks. Discard if cloudy, discoloured, or particulate.