Thymosin Alpha-1

Specifications for this product have not been published yet. Get in touch if you need the full data sheet for laboratory use.

No third-party batch reports have been uploaded for this product yet. Reports are issued by independent labs after each manufacturing batch.

What is Thymosin Alpha-1?

Thymosin Alpha-1 is a synthetic 28-amino-acid peptide acetylated at the N-terminus, with the sequence SDAAVDTSSEITTKDLKEKKEVVEEAEN, molecular formula C129H215N33O55 and CAS number 62304-98-7. It is studied in the literature as a tool compound in innate-immune signalling research. Kovalabs supplies it as a lyophilised reference compound for laboratory research use only.

Is Thymosin Alpha-1 legal to buy in the UK?

Thymosin Alpha-1 is not a controlled drug under the Misuse of Drugs Act 1971 and is not scheduled, so it may be bought and held in the UK as a laboratory reference material. It is supplied strictly for research use only and is not for human or veterinary consumption. The buyer is responsible for handling, storage and use in line with applicable law and institutional rules.

Is Thymosin Alpha-1 for human use?

No. It is supplied strictly for laboratory research use only. It is not a licensed medicine in the UK, holds no UK marketing authorisation, and is not intended, labelled or sold for human or veterinary use. It must not be used as a medicine. The milligram strength on the vial is a product specification, not a usage instruction.

What is the difference between Thymosin Alpha-1 and TB-500?

They share the word thymosin but are not variants of one compound. Thymosin Alpha-1 is a 28-residue acetylated peptide studied in innate-immune signalling research. TB-500 is a short synthetic fragment associated with thymosin beta-4, a structurally unrelated protein studied in tissue-repair and cell-migration research. They belong to different families and are sold as separate reference materials with separate certificates.

Why is Thymosin Alpha-1 also written as alpha-1 thymosin or Ta1?

All three refer to the same 28-residue acetylated sequence, CAS 62304-98-7. The word order varies between catalogues and the abbreviation Ta1 is common in the literature, which is why the same molecule appears under several spellings. Matching the CAS number and the batch certificate rather than the spelling is the reliable way to confirm identity.

What purity is the Thymosin Alpha-1 tested to?

Every batch is released only after independent analytical testing, with purity assessed by HPLC at 99% or higher and identity confirmed against the expected mass for C129H215N33O55. A batch-specific Certificate of Analysis accompanies the material and current documents are published on our CoAs page, so the specification can be checked against the vial before any work begins.

Why does batch testing matter more for a longer peptide?

At 28 residues, the common failure mode is a truncated or deletion sequence rather than gross contamination, and a shortfall of one residue will not be obvious from appearance or from a purity figure alone. Confirming identity against the expected mass for the full sequence is what distinguishes correctly synthesised material from a near-miss, which is why the certificate reports identity as well as purity.

Is all Thymosin Alpha-1 the same?

No. Material sold under the same name can differ substantially in identity and purity, and for a peptide of this length incomplete sequences are a real risk. Only a batch that ships with a certificate of analysis from an independent laboratory can be treated as a characterised reference compound; without one, the contents of the vial are an assertion rather than a verified specification.

How do I identify which batch I have received?

Match the compound name and the batch number printed on the vial label to the corresponding per-batch Certificate of Analysis on the CoAs page. The certificate states the identity result and the HPLC purity figure for that specific batch, so you can verify exactly what was supplied rather than relying on the product listing alone.

What does the research on Thymosin Alpha-1 investigate?

The published literature uses it as a tool compound to probe innate-immune signalling in cell-based systems, including dendritic-cell activation, a TLR9 / MyD88 / IRF7-dependent pathway described in murine models, and complement-receptor-mediated phagocytosis in human monocytes in vitro. None of that work establishes a benefit, effect, safety profile or outcome in humans.

How should Thymosin Alpha-1 be stored?

Store the lyophilised solid at -20C, kept dry and protected from light. Once reconstituted at the bench with a research solvent such as bacteriostatic water, hold the material at 2-8C. Storage guidance describes handling of a laboratory reference material and is not instruction for any use in a human or animal.

What is Thymosin Alpha-1 supplied as?

It is supplied as a white to off-white lyophilised solid in a sealed vial, sold per vial and despatched from the UK. It is intended to be reconstituted at the bench with a research solvent such as bacteriostatic water, which Kovalabs stocks as a separate research consumable. The stated milligram figure is a product specification only.

Can I buy Thymosin Alpha-1 in the UK from Kovalabs?

Yes. Kovalabs supplies Thymosin Alpha-1 in the UK as a research chemical for laboratory use only, despatched from the UK with a batch-specific certificate of analysis. It is not sold for human or veterinary consumption and is not a licensed medicine in the UK; the buyer is responsible for compliant handling under their own obligations.