5-Amino-1MQ

Specifications for this product have not been published yet. Get in touch if you need the full data sheet for laboratory use.

What is 5-Amino-1MQ?

5-Amino-1MQ is 5-amino-1-methylquinolinium, a small-molecule quinolinium salt supplied as the iodide with molecular formula C10H11IN2 and CAS number 42464-96-0. It is characterised in the medicinal-chemistry literature as an inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). Kovalabs supplies it as a reference compound for laboratory research use only.

Is 5-Amino-1MQ a peptide?

No. It is a synthetic heterocyclic small molecule, not a peptide, which makes it unusual within this catalogue. That distinction is practical rather than pedantic: it affects solubility, how the material is handled and how an identity assay is run, and it means peptide-specific specifications such as net peptide content do not apply to it.

Is 5-Amino-1MQ legal to buy in the UK?

5-Amino-1MQ is not a controlled drug under the Misuse of Drugs Act 1971 and is not scheduled, so it may be bought and held in the UK as a laboratory reference material. It is supplied strictly for research use only, is not a food or food supplement, and is not for human or veterinary consumption. The buyer is responsible for compliant handling.

Is 5-Amino-1MQ for human use?

No. It is supplied strictly for laboratory research use only. It is not a licensed medicine, holds no marketing authorisation, is not a food, food supplement or novel food, and is not intended, labelled or sold for human or veterinary use. The milligram strength on the vial is a product specification, not a usage instruction.

What is the difference between the iodide salt and the free cation?

They are different chemical entities with different formula weights and separate CAS entries: the iodide salt is C10H11IN2 at 286.11 g/mol under CAS 42464-96-0, while the free cation is C10H11N2+ at 159.21 g/mol under CAS 685079-15-6. Kovalabs supplies the iodide salt, and the certificate of analysis identifies which form was assayed so a stated milligram figure can be read correctly.

What does NNMT do?

Nicotinamide N-methyltransferase is an enzyme that transfers a methyl group to nicotinamide. Because nicotinamide is a precursor within the NAD+ salvage pathway, the enzyme sits at an intersection of that pathway and cellular methylation balance, which is why inhibitors of it are used as tool compounds to probe how the pathway is regulated in model systems.

What purity is the 5-Amino-1MQ tested to?

Every batch is released only after independent analytical testing, with purity assessed by HPLC at 99% or higher and identity confirmed against the expected mass for the supplied salt. A batch-specific Certificate of Analysis accompanies the material and current documents are published on our CoAs page, so the specification can be checked against the vial before any work begins.

Is all 5-Amino-1MQ the same?

No. Beyond ordinary variation in purity, material is sold as either the free cation or a salt, and the two have different formula weights, so a milligram figure means different things depending on which form is in the vial. Only a batch with a certificate of analysis from an independent laboratory states both the identity and the purity of what was actually supplied.

How do I identify which batch I have received?

Match the compound name and the batch number printed on the vial label to the corresponding per-batch Certificate of Analysis on the CoAs page. The certificate states the identity result and the HPLC purity figure for that specific batch, so you can verify exactly what was supplied rather than relying on the product listing alone.

What does the research on 5-Amino-1MQ investigate?

The published literature examines it within structure-activity programmes developing small-molecule NNMT inhibitors, characterising potency against the isolated enzyme, selectivity against related methyltransferases and membrane permeability in cell-based assays. None of that work establishes a benefit, effect, safety profile or outcome in humans.

How should 5-Amino-1MQ be stored?

Store the solid at -20C, kept dry and protected from light. Hold reconstituted material at 2-8C and keep it protected from light, since quinolinium salts are photosensitive. Storage guidance describes handling of a laboratory reference material and is not instruction for any use in a human or animal.

What is 5-Amino-1MQ supplied as?

It is supplied as a solid in a sealed vial, sold per vial and despatched from the UK, for reconstitution at the bench with an appropriate research solvent. Because it is a small molecule rather than a peptide, solvent choice differs from the peptides in this catalogue and is a matter for the researcher's own method.

Can I buy 5-Amino-1MQ in the UK from Kovalabs?

Yes. Kovalabs supplies 5-Amino-1MQ in the UK as a research chemical for laboratory use only, despatched from the UK with a batch-specific certificate of analysis. It is not sold for human or veterinary consumption and is not a licensed medicine; the buyer is responsible for compliant handling under their own obligations.

No third-party batch reports have been uploaded for this product yet. Reports are issued by independent labs after each manufacturing batch.