SS-31

2D structure

Product name

SS-31

Synonyms

Elamipretide, MTP-131

Sequence

D-Arg-Dmt-Lys-Phe-NH2

Molecular formula

C32H49N9O5

Molecular weight

639.8 g/mol

CAS number

736992-21-5

PubChem CID

11764719

Purity

>= 99% (HPLC)

Form

Lyophilised powder

Appearance

White to off-white solid

Solubility

Bacteriostatic water

Storage

Lyophilised: store at -20C, dry and light-protected. Reconstituted: 2-8C.

No third-party batch reports have been uploaded for this product yet. Reports are issued by independent labs after each manufacturing batch.

What is SS-31?

SS-31 is a synthetic, cell-permeable tetrapeptide with the sequence D-Arg-Dmt-Lys-Phe-NH2, also known as elamipretide and MTP-131. Its molecular formula is C32H49N9O5, molecular weight 639.8 g/mol, CAS number 736992-21-5 and PubChem CID 11764719. Kovalabs supplies it as a lyophilised research-grade solid for laboratory use only.

Is SS-31 a peptide?

Yes. SS-31 is a defined tetrapeptide, meaning it is built from four amino-acid residues in the sequence D-Arg-Dmt-Lys-Phe-NH2. It is a synthetic, cell-permeable small-molecule peptide rather than a botanical extract or a simple inorganic compound, and it is supplied here purely as a reference material for non-clinical research.

Is SS-31 the same as elamipretide?

SS-31 and elamipretide are two names for the same molecule, which is also designated MTP-131. The material sold here is a research chemical supplied for laboratory use only. It is not a licensed medicine and must not be used as one. It is not intended to treat, diagnose or affect any condition in humans or animals, and the milligram strength on the vial is a product specification rather than a usage instruction.

Is SS-31 legal in the UK?

SS-31 is not a controlled drug under the Misuse of Drugs Act 1971 and is not scheduled under UK controlled-substance law. It is supplied strictly as a research chemical for laboratory use, not for human or veterinary consumption, and it is not a licensed medicine. The purchaser is responsible for complying with all applicable laws covering its handling, storage and use.

Is SS-31 for human use?

No. SS-31 is supplied solely as a research chemical for in-vitro and laboratory investigation. It is not for human or veterinary use, is not a dietary supplement and is not a licensed medicine. No human or veterinary application is intended or implied. It must only be handled by qualified persons in an appropriate research setting.

Has SS-31 been shown to be safe or effective in humans?

No. We make no safety or efficacy claims. Published work on SS-31 (elamipretide) consists of pre-clinical observations in laboratory, in-vitro and animal-model systems. None of this establishes any benefit, effect or outcome in humans, and SS-31 is not a licensed medicine. It is supplied only as a reference compound for non-clinical research.

What does the research on SS-31 investigate?

The literature studies SS-31 as a mitochondria-targeted tetrapeptide, including its reported association with cardiolipin and mitochondrial bioenergetics, in laboratory and animal-model systems. These are research-context findings only and do not demonstrate any human effect. For a referenced overview see our SS-31 (elamipretide) research monograph; the product itself is supplied for laboratory research use only.

Is all SS-31 the same?

No. Material sold under the SS-31 name can vary in purity and identity. Each Kovalabs batch is released only after independent HPLC testing at >= 99% purity, with identity confirmed against the expected mass. Checking the batch-specific Certificate of Analysis against CAS 736992-21-5 and CID 11764719 is the only reliable way to verify what a vial contains.

What are the molecular identifiers for SS-31?

SS-31 has the molecular formula C32H49N9O5, a molecular weight of 639.8 g/mol and the sequence D-Arg-Dmt-Lys-Phe-NH2. It is registered under CAS number 736992-21-5 and PubChem CID 11764719, with the synonyms elamipretide and MTP-131. These identifiers should be matched against the Certificate of Analysis to confirm a batch's identity.

How is SS-31 supplied and reconstituted?

SS-31 is supplied as a white to off-white lyophilised powder. For laboratory work it is soluble in bacteriostatic water, which is added to prepare stock solutions for in-vitro research. Kovalabs stocks bacteriostatic water as a separate research reagent. Reconstitution is a laboratory preparation step only; the material is not for human or veterinary use.

How should SS-31 be stored?

Store the lyophilised SS-31 powder at -20C, kept dry and protected from light, where it remains stable for extended periods. Once reconstituted in bacteriostatic water, hold the solution at 2-8C and protect it from repeated freeze-thaw cycles to preserve peptide integrity. Always follow your laboratory's standard handling procedures for research peptides.

Does SS-31 come with a Certificate of Analysis?

Yes. Every batch ships with access to a batch-specific Certificate of Analysis reporting HPLC purity (>= 99%) and identity confirmation against the expected mass for C32H49N9O5. The CoA lets you verify the molecule against its recorded identifiers before any research use. Supporting documentation is available on our Certificates of Analysis page.

Where can I buy SS-31 in the UK?

Kovalabs supplies SS-31 (elamipretide) as a research-grade lyophilised peptide with batch CoA documentation and UK despatch. It is sold strictly for laboratory research use only and is not for human or veterinary consumption. Confirm the listed CAS number, PubChem CID and HPLC purity against the current Certificate of Analysis when ordering.

How does SS-31 differ from other cellular research peptides?

SS-31 is a distinct mitochondria-targeted tetrapeptide (D-Arg-Dmt-Lys-Phe-NH2) and is chemically separate from other cellular research compounds such as NAD+, glutathione and epithalon. Each has its own identifiers and Certificate of Analysis. All are supplied by Kovalabs solely as reference materials for non-clinical laboratory research, with no human or veterinary application intended.