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Cellular & Senescence
Epithalon
- Purity
- >= 99% (HPLC)
- Form
- Lyophilised powder
- Origin
- United States
Manufactured for laboratory research. Not for human or veterinary use. Read full disclaimer →
Epithalon (epitalon) is a synthetic tetrapeptide studied in research into telomerase activity and cellular-senescence pathways in experimental models.
- Purity >= 99% (HPLC)
- Supplied as a lyophilised powder
- Independent batch identity and purity testing
- For laboratory research use only; not for human or veterinary use
What is Epithalon (Epitalon)?
Epithalon (also spelled Epitalon) is a synthetic tetrapeptide with the amino acid sequence Ala-Glu-Asp-Gly, modelled on the pineal peptide preparation epithalamin. It has the molecular formula C14H22N4O9, a molecular weight of 390.35 g/mol and CAS number 307297-39-8. It is supplied here as a lyophilised solid reference material for laboratory research use only.
The two spellings, Epithalon and Epitalon, refer to the same Ala-Glu-Asp-Gly tetrapeptide; they are used interchangeably across the literature and supply listings. This is a research chemical and is not a medicine, supplement or food.
Is Epithalon legal in the UK?
Epithalon is not a controlled drug under the Misuse of Drugs Act 1971, and it is not a licensed medicine in the UK. It is supplied strictly as a research chemical for laboratory use only, and it is not for human or veterinary consumption. The purchaser is responsible for handling, storage and compliance with all applicable local regulations. See our research disclaimer for the full terms of supply.
How is identity and quality assured?
Each batch is released only after independent identity and purity testing. Purity is assessed by HPLC at 99% or higher, and identity is confirmed against the expected mass for the Ala-Glu-Asp-Gly sequence (CAS 307297-39-8, PubChem CID 219042). Not all material listed as Epithalon is equivalent: a verifiable certificate of analysis is the only way to confirm what a given vial contains. Batch documentation is available via our certificates of analysis.
What does the research on Epithalon investigate?
The published literature on Epithalon sits in the pineal-peptide research area and examines the Ala-Glu-Asp-Gly tetrapeptide in pre-clinical, in-vitro and animal-model systems, including work referencing telomere biology and cellular-senescence models. None of this establishes a benefit, effect or outcome in humans, and Epithalon is not a licensed medicine. For the mechanistic and study-design detail, see our monograph: Epithalon and telomerase research.
Synthesis and supply
Epithalon is supplied as a lyophilised (freeze-dried) white to off-white powder and is soluble in bacteriostatic water for reconstitution in the laboratory. Store the lyophilised solid at -20C, kept dry and protected from light; hold reconstituted material at 2-8C. It is listed in our cellular research category alongside related reference compounds including NAD+, Glutathione and SS-31. For laboratory research use only; not for human or veterinary use.
- 2D structure
- Product name
- Epithalon
- Synonyms
- Epitalon, Ala-Glu-Asp-Gly
- Sequence
- Ala-Glu-Asp-Gly
- Molecular formula
- C14H22N4O9
- Molecular weight
- 390.35 g/mol
- CAS number
- 307297-39-8
- PubChem CID
- 219042
- Purity
- >= 99% (HPLC)
- Form
- Lyophilised powder
- Appearance
- White to off-white solid
- Solubility
- Bacteriostatic water
- Storage
- Lyophilised: store at -20C, dry and light-protected. Reconstituted: 2-8C.
- What is Epithalon?
- Epithalon (also spelled Epitalon) is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly, modelled on the pineal peptide preparation epithalamin. It has the molecular formula C14H22N4O9, a molecular weight of 390.35 g/mol and CAS number 307297-39-8. It is supplied as a lyophilised reference material for laboratory research use only, and it is not a medicine, supplement or food.
- Is Epithalon the same as Epitalon?
- Yes. Epithalon and Epitalon are two spellings of the same Ala-Glu-Asp-Gly tetrapeptide and are used interchangeably across the research literature and supply listings. There is no chemical difference between the two names; both refer to the compound with CAS number 307297-39-8 and PubChem CID 219042.
- Is Epithalon legal in the UK?
- Epithalon is not a controlled drug under the Misuse of Drugs Act 1971 and is not a licensed medicine in the UK. It is supplied strictly as a research chemical for laboratory use only and is not for human or veterinary consumption. The purchaser is responsible for lawful handling, storage and use, and for compliance with all applicable local regulations.
- Is Epithalon for human use?
- No. Epithalon is supplied solely as a research chemical for laboratory use. It is not for human or veterinary consumption and no human or veterinary application is intended or implied. It is not a medicine and has not been approved for use in or on the body in any form.
- Has Epithalon been shown to be safe or effective in humans?
- No. The published work on Epithalon sits in pre-clinical, in-vitro and animal-model research and does not establish any benefit, effect, safety or efficacy outcome in humans. Epithalon is not a licensed medicine and is supplied as a reference compound for non-clinical laboratory investigation only.
- What does the research on Epithalon investigate?
- The literature examines the Ala-Glu-Asp-Gly tetrapeptide within the pineal-peptide research area, including pre-clinical work referencing telomere biology and cellular-senescence model systems. These are laboratory observations only and do not demonstrate any effect or outcome in humans. Mechanistic and study-design detail is covered in our Epithalon and telomerase research monograph.
- What are the molecular identifiers for Epithalon?
- Epithalon has the amino acid sequence Ala-Glu-Asp-Gly, the molecular formula C14H22N4O9 and a molecular weight of 390.35 g/mol. Its CAS number is 307297-39-8 and its PubChem CID is 219042. These identifiers are listed on the certificate of analysis supplied with each batch.
- Is all Epithalon the same?
- No. Material listed under the Epithalon or Epitalon name can vary in identity and purity between suppliers. The only reliable way to confirm what a vial contains is a verifiable certificate of analysis. Our batches are released after independent HPLC purity testing and mass-confirmed identity against the Ala-Glu-Asp-Gly sequence.
- How is Epithalon supplied and reconstituted?
- Epithalon is supplied as a lyophilised (freeze-dried) white to off-white powder. For laboratory work it is soluble in bacteriostatic water, which can be used to reconstitute the powder. Bacteriostatic water is available separately. Reconstitution is a laboratory handling step only and does not imply any human or veterinary application.
- How should Epithalon be stored?
- Store the lyophilised solid at -20C, kept dry and protected from light. Once reconstituted, hold the material at 2-8C. Proper cold, dry, light-protected storage helps maintain the integrity of the lyophilised peptide for laboratory research use.
- What purity is the Epithalon and is a certificate of analysis available?
- Each batch is tested to 99% purity or higher by HPLC, with identity confirmed against the expected mass for the Ala-Glu-Asp-Gly sequence. A certificate of analysis documenting batch identity and purity is available for every batch via our certificates of analysis page.
- Is Epithalon a peptide?
- Yes. Epithalon is a tetrapeptide, meaning it is a short chain of four amino acids: alanine, glutamic acid, aspartic acid and glycine (Ala-Glu-Asp-Gly). It is a synthetic peptide modelled on the natural pineal peptide preparation epithalamin and is supplied as a lyophilised reference compound for laboratory research use only.
- Can I buy Epithalon in the UK?
- Yes. Kovalabs supplies Epithalon (Epitalon) as a research chemical with UK despatch. It is sold for laboratory research use only and is not for human or veterinary consumption. Each order ships with batch documentation, and a certificate of analysis is available confirming identity and purity.
- How does Epithalon differ from other cellular research compounds?
- Epithalon is a small tetrapeptide (Ala-Glu-Asp-Gly) distinct from other reference compounds in the cellular research category such as NAD+, Glutathione and SS-31, which differ in structure and the research areas they are studied within. All are supplied as research chemicals for laboratory use only and none is a medicine or intended for human use.
No third-party batch reports have been uploaded for this product yet. Reports are issued by independent labs after each manufacturing batch.
Calculator
Research planning only
Concentration5.00 mg/ml
Volume to draw0.050 ml
Insulin syringe (100 IU/ml)
5.0units
For research planning only. Not medical, dosing, or therapeutic advice. All Kovalabs products are research-use-only.
Store unreconstituted vials at −20°C for long-term, or refrigerated at 2-8°C for short-term use. Avoid repeated freeze-thaw cycles.
Reconstitute with bacteriostatic water down the inside wall of the vial; gently swirl to dissolve. Do not shake.
Once reconstituted, refrigerate at 2-8°C and use within 2-4 weeks. Discard if cloudy, discoloured, or particulate.