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Cellular & Senescence
Glutathione
- Purity
- >= 99% (HPLC)
- Form
- Lyophilised powder
- Origin
- United States
Manufactured for laboratory research. Not for human or veterinary use. Read full disclaimer →
Glutathione is a tripeptide (gamma-glutamyl-cysteinyl-glycine) studied in research into redox balance and oxidative-stress pathways in experimental models.
- Purity >= 99% (HPLC)
- Supplied as a lyophilised powder
- Independent batch identity and purity testing
- For laboratory research use only; not for human or veterinary use
What is glutathione?
Glutathione (GSH) is a tripeptide formed from glutamate, cysteine and glycine, with the sequence gamma-Glu-Cys-Gly. Its molecular formula is C10H17N3O6S and its molecular weight is 307.33 g/mol (CAS 70-18-8). It is the principal endogenous low-molecular-weight thiol in cells and is the reduced form, sometimes written as L-glutathione reduced. Kovalabs supplies it as a lyophilised solid for laboratory research.
The free thiol on the cysteine residue makes glutathione a common reference reagent in redox biochemistry. It is distinct from its oxidised dimer (GSSG); this product is the reduced monomer. It is a tripeptide, not a steroid, hormone or vitamin, and is catalogued in our cellular research range.
Is glutathione legal in the UK?
Glutathione is not a controlled drug under the Misuse of Drugs Act 1971 and is not scheduled. Kovalabs supplies it strictly as a research chemical for in-vitro and laboratory use, not for human or veterinary consumption and not as a food supplement, cosmetic or medicine. It is not a licensed medicinal product. Purchasers are responsible for compliance with the applicable rules in their jurisdiction. Full terms are set out in our research disclaimer.
How is identity and quality assured?
Every batch is released after independent identity and purity testing. Purity is assessed by HPLC at 99% or higher, and identity is confirmed against the expected mass and against the published identifiers: CAS 70-18-8, PubChem CID 124886, and InChIKey RWSXRVCMGQZWBV-WDSKDSINSA-N. Not all material sold under the glutathione name is the same grade, which is why a batch-specific certificate of analysis matters. Documentation is published on our certificates of analysis page.
What does the research on glutathione investigate?
The published literature investigates glutathione in cellular redox balance, glutathione-dependent conjugation chemistry, and oxidative-stress model systems, almost all of it in in-vitro or animal settings. None of this establishes a benefit, effect or outcome in humans, and glutathione is not a licensed medicine. We do not make therapeutic, cosmetic or supplement claims. The mechanistic and study-design detail is covered in our glutathione research monograph.
Synthesis and supply
Glutathione is supplied as a lyophilised white to off-white powder. For bench work it is reconstituted in a suitable research solvent such as bacteriostatic water, which Kovalabs also stocks. Store the lyophilised solid at -20C, kept dry and protected from light; hold reconstituted material at 2-8C. Researchers comparing thiol and redox reference materials also order NAD, SS-31 and Epithalon. For laboratory research use only; not for human or veterinary use.
External resources for researchers
- 2D structure
- Product name
- Glutathione
- Synonyms
- GSH, L-Glutathione reduced
- Sequence
- gamma-Glu-Cys-Gly
- Molecular formula
- C10H17N3O6S
- Molecular weight
- 307.33 g/mol
- InChIKey
- RWSXRVCMGQZWBV-WDSKDSINSA-N
- CAS number
- 70-18-8
- PubChem CID
- 124886
- Purity
- >= 99% (HPLC)
- Form
- Lyophilised powder
- Appearance
- White to off-white solid
- Solubility
- Bacteriostatic water
- Storage
- Lyophilised: store at -20C, dry and light-protected. Reconstituted: 2-8C.
- What is glutathione?
- Glutathione (GSH) is a tripeptide of glutamate, cysteine and glycine with the sequence gamma-Glu-Cys-Gly. Its formula is C10H17N3O6S, its molecular weight is 307.33 g/mol, and its CAS number is 70-18-8. It is the principal endogenous low-molecular-weight thiol in cells and is supplied here as the reduced form, a lyophilised solid for laboratory research.
- What is reduced glutathione, and how does it differ from GSSG?
- Reduced glutathione is the monomeric form carrying a free thiol on its cysteine residue (sometimes written L-glutathione reduced). Its oxidised counterpart, GSSG, is a dimer formed when two glutathione molecules link through a disulphide bond. This product is the reduced monomer, CAS 70-18-8, supplied as a reference compound for redox biochemistry.
- Is glutathione legal in the UK?
- Glutathione is not a controlled drug under the Misuse of Drugs Act 1971 and is not scheduled. Kovalabs supplies it strictly as a research chemical for laboratory use, not for human or veterinary consumption and not as a food supplement, cosmetic or medicine. Buyers are responsible for compliance with the rules in their jurisdiction.
- Is this glutathione intended for human use?
- No. This material is supplied solely as a reference compound for non-clinical laboratory research. It is not a food supplement, cosmetic or medicine, and no human or veterinary application is intended or implied. It must not be consumed or administered to people or animals.
- Has glutathione been shown to be safe or effective in humans?
- We make no such claims. The published literature investigates glutathione in in-vitro and animal model systems studying redox balance and conjugation chemistry. None of that establishes a benefit, effect, safety or outcome in humans, and glutathione is not a licensed medicine. Study-design detail is covered in our glutathione research monograph.
- Is all glutathione the same?
- No. Material sold under the glutathione name varies in grade and purity. Kovalabs releases each batch only after independent identity and purity testing, with purity at 99% or higher by HPLC and identity confirmed against the expected mass and identifiers. A batch-specific certificate of analysis is the way to verify what you receive.
- What are the molecular identifiers for glutathione?
- Glutathione has CAS number 70-18-8, molecular formula C10H17N3O6S, molecular weight 307.33 g/mol, PubChem CID 124886, and InChIKey RWSXRVCMGQZWBV-WDSKDSINSA-N. Its sequence is gamma-Glu-Cys-Gly. These identifiers let you confirm identity against PubChem and the certificate of analysis.
- Is glutathione a peptide, a steroid or a vitamin?
- Glutathione is a tripeptide: three amino acids (glutamate, cysteine, glycine) joined by peptide bonds, including an unusual gamma linkage at the glutamate. It is not a steroid, not a hormone and not a vitamin. It is the principal endogenous low-molecular-weight thiol in cells, catalogued in our cellular research range.
- How is glutathione supplied and reconstituted?
- It is supplied as a lyophilised white to off-white powder. For bench work it is reconstituted in a suitable research solvent such as bacteriostatic water, which Kovalabs also stocks. This is a laboratory preparation step only; the material is not for human or veterinary use.
- How should glutathione be stored?
- Store the lyophilised solid at -20C, kept dry and protected from light. Hold reconstituted material at 2-8C. Glutathione's free thiol is sensitive to oxidation, so minimising air, moisture and light exposure helps preserve the reduced form for laboratory work.
- Do you provide a certificate of analysis for glutathione?
- Yes. Each batch is released after independent identity and purity testing, and a batch-specific certificate of analysis documents HPLC purity (99% or higher) and identity confirmation. Documentation is available on our certificates of analysis page so you can verify the exact lot you receive.
- Where can I buy glutathione in the UK?
- Kovalabs supplies glutathione (CAS 70-18-8) from the UK with batch certificates of analysis and UK despatch, for laboratory research use only. It is the reduced GSH tripeptide as a lyophilised powder. It is not sold for human consumption or as a supplement, cosmetic or medicine.
- How does glutathione compare to other cellular research compounds?
- Glutathione is a thiol-bearing tripeptide used as a redox reference reagent, which is a different chemical class from compounds such as NAD, SS-31 or Epithalon. Researchers assembling a redox and cellular toolkit often hold several of these alongside one another. Each is supplied as a distinct research chemical, not for human use.
- Is glutathione the same as a glutathione supplement?
- No. This is a research-grade reference chemical supplied for laboratory use, not a dietary supplement, tablet or capsule. It carries no nutritional or health positioning and is not formulated, labelled or sold for human consumption. It is the glutathione molecule itself, characterised for bench research.
No third-party batch reports have been uploaded for this product yet. Reports are issued by independent labs after each manufacturing batch.
Calculator
Research planning only
Concentration750.00 mg/ml
Volume to draw0.000 ml
Insulin syringe (100 IU/ml)
0.0units
For research planning only. Not medical, dosing, or therapeutic advice. All Kovalabs products are research-use-only.
Store unreconstituted vials at −20°C for long-term, or refrigerated at 2-8°C for short-term use. Avoid repeated freeze-thaw cycles.
Reconstitute with bacteriostatic water down the inside wall of the vial; gently swirl to dissolve. Do not shake.
Once reconstituted, refrigerate at 2-8°C and use within 2-4 weeks. Discard if cloudy, discoloured, or particulate.